Forschungsprojekte

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• Nano-Q

  Aim of this cooperation project is the development of a mercury sensor system for personal air monitoring (PAM). The sensor system is based on applications of nanogranular materials. The major tasks are the construction of a mercury test bench for the adjustment of lowest mercury concentrations and the characterization of the mercury sensors.

  Jahr: 2016

  Förderung: This project is sponsored by the Federal Ministry of Education and Research. (13XP5011B)
• ESI-IMS

  Aim of this research project is the detection and analysis of pesticide and drug residues present in ground and surface water. Electrospray ionization (ESI) is a commonly used ionization method for the analysis of liquids. We coupled an electrospray ionization source with a 75mm desolvation tube to our high resolution ion mobility spectrometer with a 75mm drift tube length. One major advantage of our setup is that the desolvation region of the ESI-IMS can be heated separately from the drift region. With this setup we reach e.g. a resolving power of R=100 for tetraalkylammonium halides and at a water content of 50% and after 2s of averaging a LOD of 4 µg/l for bentazon.

  Jahr: 2016
• Closed gas loop, high-resolution IMS with gas chromatographic pre-separation for breath gas analysis

  In many breath gas analysis applications, real-time and bed-site analysis is required to achieve true applicability for clinical diagnosis. Thus, we built a compact, closed gas loop, high-resolution GC-IMS. The ion mobility spectrometer achieves a mobility resolution of R=90. The GC-IMS is equipped with a filter re-circulation system providing a continuous supply of dry and clean drift gas, so that no external supply is needed. Hence, the entire system fits in a 19″ housing (6 RU height).

  Jahr: 2016
• MiniLAB

  The aim of the cooperation project MiniLAB is the development of a portable instrument for fast on-site monitoring and detection of pollutants in water based on nano high performance liquid chromatography (nano-HPLC) and electrospray ionization (ESI) ion mobility spectrometry (IMS). The main tasks of the subproject are the realization of a high voltage isolated data acquisition as well as the control of the ESI parameters during a run of a solvent gradient.

  Jahr: 2019

  Förderung: Supported by the German Federal Ministry of Economics and Technology (BMWi) upon decision of the German Bundestag, Grant 20666 N
• GC-IMS measurements of volatile anaesthetics

  This project focuses on all topics related to trigger-free anaesthesia for patients threatened by malignant hyperthermia. With our GC-IMS, especially medical devices and indoor air will be examined for traces of volatile anaesthetics. For example, these substances can be detected in an average concentration of 120 ppb in postanaesthesia care units.

  Jahr: 2020
• Ultra-fast detection in droplet microfluidics using ion mobility spectrometry

  The aim of this project is the fast, label-free detection of individual droplets in microfluidic chip systems using IMS. The challenge is to explore the possibilities and limits of this promising detection method for droplet microfluidics and to enable the label-free detection of individual droplet contents at high throughput.

  Jahr: 2021

  Förderung: This research is founded by the German Research Foundation (DFG)
• Coated Blade Spray Ion Mobility Spectrometry

  Coated Blade Spray (CBS) is a microextraction technology with blades that serve as both the extraction device and the electrospray ionization (ESI) emitter. This project focuses on coupling CBS with our ESI-IMS. The capability of CBS-IMS to detect benzodiazepines and ketamine in drinks and the pesticide isoproturon in water samples has been demonstrated.

  Jahr: 2022
• Split-ring resonator as detector for liquid and ion chromatography

  The analysis of food and drugs, as well as the monitoring of chemical processes and bioreactors, requires the use of high-performance liquid chromatography (HPLC) and ion chromatography. These processes are best conducted with universal, cost-effective, and sensitive detectors. This project focuses on the use of a split-ring resonator, which detects changes in the electrical and dielectric properties of the eluate from liquid chromatography or ion chromatography by monitoring the amplitude of the transmitted signal using an envelope detector.

  Jahr: 2023